A chip-scale microscope for high-throughput fluorescence imaging

Conventional light microscopy has been instrumental for studying cells and microorganisms; fluorescence microscopy enabled visualization of even smaller cell features by selectively adding fluorescent labels to molecules. These microscopes are often comprise bulky and expensive systems that require regular maintenance to keep the lenses aligned. Additionally, they need to strike a compromise between device size, the size of the field of view, and resolution. For scientists to see more detail, larger optical components are required, but this causes the field of view to decrease.Conventional light microscopy has been instrumental for studying cells and microorganisms; fluorescence microscopy enabled visualization of even smaller cell features by selectively adding fluorescent labels to molecules. These microscopes are often comprise bulky and expensive systems that require regular maintenance to keep the lenses aligned. Additionally, they need to strike a compromise between device size, the size of the field of view, and resolution. For scientists to see more detail, larger optical components are required, but this causes the field of view to decrease.Read More

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